skin science

Regenerative aesthetics - activating beauty from within

We know the body has an incredible ability to heal itself—and regenerative aesthetics taps into that natural potential. By working with your biology, these treatments reduce the need for surgery or synthetic ingredients, instead aiming to restore a naturally youthful, rejuvenated look. As this area of aesthetics continues to evolve, new technologies are constantly being developed to harness the body’s regenerative power—making it harder to know where to start.

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2025 - 10 - 23

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We know the body has an incredible ability to heal itself—and regenerative aesthetics taps into that natural potential. By working with your biology, these treatments reduce the need for surgery or synthetic ingredients, instead aiming to restore a naturally youthful, rejuvenated look. As this area of aesthetics continues to evolve, new technologies are constantly being developed to harness the body’s regenerative power—making it harder to know where to start.

Let us break down these new technologies and explore the most common treatments, so you know your exosomes from your biostimulators!

What is regenerative aesthetics?

Before we dive in, we have to understand the science of our skin. You’ve probably heard of collagen and elastin–these are foundational building blocks of your skin, responsible for its structure, elasticity and flexibility. When they are abundant, it keeps your skin supple and youthful-looking. But these proteins are not endless. Our bodies produce a lot of elastin as a child, but this declines significantly after adolescence.1 As we age, our ability to replace our natural collagen declines by approximately 1%-1.5% each year.2 Other environmental factors can also speed up the decline of our collagen, for example, sun exposure, smoking and diet. This all contributes to increased signs of aging like fine lines, sagging, and volume loss.

Here is where regenerative aesthetics is changing the game. Instead of relying on artificial or synthetic ingredients, or the need for surgery, regenerative aesthetics works with our bodies' natural processes. Regenerative aesthetics addresses the signs of aging and improves skin appearance, by using your skin’s natural healing mechanism. Rather than correct the symptoms of aging, they get right to the cause, using natural and holistic methods. 

Common regenerative aesthetic treatments

Platelet-Rich Plasma (PRP) Therapy

What is it?

This treatment has grown in popularity over the last decade and is commonly nicknamed “the vampire facial”. This is because PRP uses a small amount of your own blood and isolates a key component from it–your platelets. 
 

How does it work?

Platelets are perfect for the job because they play a central role in creating blood clots, repairing wounds and tissue regeneration. Once your platelets are isolated, they are injected back into selected areas of your skin and start to release growth factors.
 

What results can I expect?

These growth factors get to work stimulating collagen production and tissue regeneration. These skin changes improve the texture and elasticity of your skin, to deliver rejuvenated and youthful-looking results.3

Exosome treatment

What is it?

You’d be forgiven for not knowing what an exosome is. To understand this treatment, we need to go to the molecular level: your individual cells. The cells in your body communicate with each other by releasing vesicles called exosomes. These exosomes contain protein, fats and DNA which travel between your cells.4 But how is this related to your skin? 

How does it work?

Exosomes also contain bioactive molecules such as growth factors and cytokines, amongst others, which repair and regenerate skin.4 These exosomes can be delivered through microneedling, an injection into the skin, or applied topically to the surface of the skin.5

What results can I expect?

Once administered, the exosomes kick start your natural regenerative processes which promote the production of collagen and elastin. These are key to combat signs of aging such as fine lines and sagging tissue, to leave your skin rejuvenated.4

Biostimulators and threads

What is it?

Biostimulators are made from materials that are biocompatible with your body. This means when injected into the skin, they are naturally reabsorbed into the body. One of the most common types of biostimulator are threads. These are made from the same material as sutures which have been used for years to close wounds.

How does it work?

During a threads treatment, the thread is inserted beneath the skin and begins regenerating collagen for smoother, firmer skin.6

However, not all threads were created equal. Definisse Threads are made from a modern polymer, P(LA-CL), which regenerates collagen over a longer period compared to other materials.7

What results can I expect?

By stimulating fibroblasts, the collagen factories in your skin, Definisse Threads tighten and support the skin, reducing signs of aging for revitalised skin.7

But they don’t stop there. As Definisse Threads break down and are reabsorbed, they also stimulate hyaluronic acid, the ultimate skin moisturiser, so your skin appears supple and hydrated.7

Definisse Threads are also long-lasting, continuing to boost collagen even after they’ve been reabsorbed into the body.7

With Definisse Threads, you can enjoy long-lasting results, few treatment sessions and a low risk of side effects.8

Discover our biostimulator threads and activate beauty from within. 

Why choose regenerative aesthetics?

Long-lasting results: Regenerative aesthetics stimulate your skin’s natural healing processes, with results building over time. 

Natural-looking
enhancements: By using your skin’s natural processes, regenerative treatments produce more natural-looking results that enhance your unique beauty. 

Low risk of side effects
: In place of synthetic ingredients, some regenerative aesthetic treatments use ingredients from your own body, reducing the chance of an adverse reaction. 

Activate beauty from within

If you’re considering a holistic, natural treatment that can combat signs of aging, from prevention to subtle enhancements, regenerative aesthetics is worth considering.

Regenerative treatments are an exciting and evolving area of aesthetics–as with any procedure, discuss your treatments with your aesthetics professional to create a personalised treatment plan.

Support your body’s natural healing processes for youthful, revitalised skin and begin the search for your perfect treatment here. 

References

1. Trebacz E, Piatkowski K. Mechanical properties of elastin. Biopolymers. 2001;62(1):40–4.

2. Reilly DM, Penezini F, Errante F, Rovero P, Pascarella S. Skin collagen through the lifestages: importance for skin health and beauty. Plast Aesthet Res. 2021;8:2.

3. Asubiaro O. Platelet-rich plasma in aesthetic dermatology: current concepts, challenges, and prospects. Dermatol Ther. 2021;34(4):e14910.

4. Hajialiasghari Najafabadi A, Zarei F, Karimi M. Exosomes in skin wound healing, aging, and disease: current trends and future perspectives. J Transl Med. 2021;19(1):537.

5. Zhang B, Wang M, Gong A, Zhang X, Wu X, Zhu Y, et al. Exosome-based advancements for application in medical aesthetics. Aesthetic Plast Surg. 2022;46(1):391–402.

6. Wong V. Hanging by a thread: the role of absorbable barbed threads in facial rejuvenation. J Clin Aesthet Dermatol. 2020;13(3):28–34.

7. Wong V. The science of absorbable poly(L-lactide-co-ε-caprolactone) threads for soft tissue repositioning of the face. Aesthet Surg J. 2021;41(5):NP320–7.

8. Savoia A, Accardo C, Vannini F, Di Pasquale B, Baldi A. Outcomes in thread lift for facial rejuvenation: a study performed with Happy Lift™ revitalizing. Dermatol Ther. 2014;4(1):103–14.